FORMULATION OF HERBAL GEL HYDROGEL MICROSPHERES AND ITS APPLICATION IN SKIN REPAIR

Abstract

Herbal hydrogel microspheres represent an advanced topical drug-delivery system designed to enhance skin repair and regeneration. These formulations combine natural plant extracts with microsphere technology to achieve controlled drug release, improved stability, and enhanced penetration of herbal actives into the skin. Hydrogels provide hydration, soothing action, and an ideal moist environment for wound healing, while microspheres protect sensitive phytochemicals and reduce dosing frequency. The present work focuses on the formulation of cinnamon-loaded sodium alginate hydrogel microspheres for skin repair applications. Cinnamon possesses strong antioxidant, antimicrobial, and collagenstimulating properties that promote faster wound healing and reduce inflammation. Sodium alginate acts as a biocompatible, moisture-retaining polymer suitable for topical use. The prepared microspheres were incorporated into a Carbopol hydrogel base to improve skin compatibility and application. Despite certain limitations such as stability issues, possible skin irritation at higher concentrations, and variability in herbal composition, cinnamon-loaded alginate hydrogel microspheres show promising potential as a natural, safe, and patient-friendly system for advanced skin repair and wound management.